Authors

Katina Aleksovska, Università Cattolica del Sacro Cuore, Rome
Anna Puggina, Università Cattolica del Sacro Cuore, Rome
Luca Giraldi, Università Cattolica del Sacro Cuore, Rome
Christoph Buck, Leibniz Institute for Prevention Research and Epidemiology
Con Burns, Department of Sport, Leisure & Childhood Studies, Cork Institute of Technology, Cork, IrelandFollow
Greet Cardon, Universiteit Gent
Angela Carlin, University of Limerick
Simon Chantal, University of Valencia
Donatella Ciarapica, CREA-Research Centre for Food and Nutrition
Marco Colotto, Università Cattolica del Sacro Cuore, Rome
Giancarlo Condello, Università degli Studi di Roma "Foro Italico"
Tara Coppinger, Department of Sport, Leisure & Childhood Studies, Cork Institute of Technology, Cork, IrelandFollow
Cristina Cortis, Universita di Cassino e del Lazio Meridionale
Sara D’haese, Universiteit Gent
Marieke De Craemer, Universiteit Gent
Andrea Di Blasio, University of G. d'Annunzio Chieti and Pescara
Sylvia Hansen, Universität Stuttgart
Licia Iacoviello, Istituto Neurologico Mediterraneo Neuromed, Pozzilli
Johann Issartel, Dublin City University
Pascal Izzicupo, University of G. d'Annunzio Chieti and Pescara
Lina Jaeschke, Max Delbruck Center for Molecular Medicine
Martina Kanning, Universität Stuttgart
Aileen Kennedy, Dublin City University
Fiona Ling, University of Limerick
Agnes Luzak, Helmholtz Center Munich German Research Center for Environmental Health
Giorgio Napolitano, University of G. d'Annunzio Chieti and Pescara
Julie Anne Nazare, Université Claude Bernard Lyon 1
Camille Perchoux, Université Claude Bernard Lyon 1
Tobias Pischon, Max Delbruck Center for Molecular Medicine
Angela Polito, CREA-Research Centre for Food and Nutrition
Alessandra Sannella, Universita di Cassino e del Lazio Meridionale
Holger Schulz, Helmholtz Center Munich German Research Center for Environmental Health

ORCID

https://orcid.org/0000-0002-7251-4516

Document Type

Article

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Disciplines

Medicine and Health | Medicine and Health Sciences | Sociology | Sports Sciences

CIT Disciplines

3. MEDICAL AND HEALTH SCIENCES; 3.3 HEALTH SCIENCES; Sport and fitness sciences

Publication Details

© The Author(s). 2019.

This article was published in the journal Sports Medicine - Open on the 08 January 2019. Available at: http://dx.doi.org/10.1186/s40798-018-0173-9.

Funding

○ 1, 19, 20 MIUR: CDR2.PRIN 2010/11 COD. 2010KL2Y73_003.

○ 1 Eraweb 2: contract n. 2013-2548/001-001-EMA2 for supporting the work of Katina Aleksovska.

○ 2 Federal Ministry of Education and Research, Germany (01EA1377).

○ 3, 5, 13, 15 The Health Research Board, Ireland.

○ 8 MIUR: DEDIPAC F.S. 02.15.02 COD. B84G14000040008.

○ 11 Federal Ministry of Education and Research, Germany (01EA1374).

○ 14, 17 This project was supported by grants from the Federal Ministry of Education and Research, Germany (Bundesministerium für Bildung und Forschung, Förderkennzeichen 01EA1372C and 01EA1372E. The responsibility for the content of this manuscript lies with the authors).

○ 18 Institut National de la Recherche Agronomique (INRA), Institut National de Prévention et d’Education pour la Sante (INPES).

Abstract

Background: Despite the large number of studies and reviews available, the evidence regarding the biological determinants of physical activity (PA) is inconclusive. In this umbrella review, we summarized the current evidence on the biological determinants of PA across the life course, by pooling the results of the available systematic literature reviews (SLRs) and meta-analyses (MAs). Methods: We conducted an online search on MEDLINE, ISI Web of Science, Scopus, and SPORTDiscus databases up to January 2018. SLRs and MAs of observational studies that investigated the association between biological determinants of PA and having PA as outcome were considered eligible. The extracted data were assessed based on the importance of the determinants, the strength of evidence, and the methodological quality. Results: We identified 19 reviews of which most were of moderate methodological quality. Determinants that were studied most frequently among all ages and demonstrated evidence suggesting a positive association to PA were younger age, being male, higher health status, and higher physical fitness levels. Among adults, normal birth weight was found to be positively associated to PA with convincing strength of evidence, while findings among adolescents were inconsistent and with limited strength of evidence. Conclusions: Different social or behavioral factors may contribute to the decrease of PA with age and among females versus males, and creating programmes targeted at diverse ages, female population, and adults with abnormal birth weight is recommended. Future studies should use prospective study designs, standardized definitions of PA, and objective measurement methods of PA assessment.

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