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Herein we review the most recent advances in probiotic research and applications with particular emphasis on the novel concept of patho-biotechnology: the application of pathogen-derived (ex vivo and in vivo) stress survival strategies for the design of more technologically robust and effective probiotic cultures with improved biotechnological and clinical applications.
Sleator, R.D. & Hill, C., 2009. Rational Design of Improved Pharmabiotics. Journal of Biomedicine and Biotechnology, 2009, pp.1–7. Available at: http://dx.doi.org/10.1155/2009/275287.