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Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.



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Journal of Biomedicine and Biotechnology

R. D. Sleator is a Health Research Board (HRB) Principal Investigator. The authors wish to acknowledge the continued financial assistance of the HRB, and the Alimentary Pharmabiotic Centre (APC) through funding by Science Foundation Ireland (SFI).


Herein we review the most recent advances in probiotic research and applications with particular emphasis on the novel concept of patho-biotechnology: the application of pathogen-derived (ex vivo and in vivo) stress survival strategies for the design of more technologically robust and effective probiotic cultures with improved biotechnological and clinical applications.

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