Date of Award
2015
Document Type
Doctoral Thesis
Degree Name
Doctor of Philosophy
Department
Biological Sciences
First Advisor
Dr. Roy Sleator
Abstract
Cronobacter sakazakii is an organism which has been associated with severe life- threatening diseases in infants and neonates. Mortality rates of up to 80% have been recorded in infants infected with Cronobacter sakazakii. Infants often suffer from septicaemia, necrotising enterocolitis and meningitis as a result of infection. A characteristic feature of the opportunistic foodborne pathogen Cronobacter sakazakii is its ability to survive in extremely arid environments such as powdered infant formula, making it a dangerous opportunistic pathogen of neonates. Herein, we provide a brief overview of the pathogen; clinical manifestations, environmental reservoirs and our current understanding of stress response mechanisms and virulence factors which allow it to cause disease.
Recommended Citation
Feeney, Audrey, "Identification of the Molecular Mechanisms Governing the Osmotolerance of the Emerging Gastrointestinal Pathogen Cronobacter sakazakii" (2015). Theses [online].
Available at: https://sword.cit.ie/allthe/486
Access Level
info:eu-repo/semantics/openAccess