Date of Award


Document Type

Master Thesis

Degree Name

Masters of Science (Research)


Biological Sciences

First Advisor

Dr Aoife McCarthy

Second Advisor

Dr Fiona O'Halloran


Brewer’s Spent Grain (BSG) represents a substantial waste product of the brewing industry, with 39 million tonnes generated globally every year. To date the primary use of BSG is as animal feed but there is significant interest in identifying alternative uses for this agro-industry by-product. BSG is rich in protein and fibre and is known to contain health-promoting bioactive compounds, thus one application would be in the area of functional foods. People are living longer and as the older adult population continues to increase globally so too is the prevalence of age-related chronic conditions. Diet plays an essential role in healthy ageing and there is currently an increased demand for more convenient, affordable and healthy food options for the elderly cohort. This research aims to help reduce the environmental burden of brewery waste and add to the global demand for innovative functional food products for older adults, by investigating the bioactivity of BSG. Novel BSG fractions were generated, digested with a simulated gastrointestinal in vitro digestion (SGID) system and then screened for a range of bioactivities. The potential antioxidant, immunomodulatory and anti-obesogenic properties of the digestates were investigated using cellular and non-cellular assays. BSG-derived fractions that had significantly improved (p

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Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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